Search This Blog

Sunday, October 2, 2022

Mushrooms for MS. November 2022



                                            https://en.m.wikipedia.org/wiki/Hericium_erinaceus


Weird to think a plant, a fungi, could have benefits.  There is little to no studies done on my condition, which leads me to mushrooms, End of 2022.


My latest Diagnosis of the MS,  I have not told anybody about, as a year has gone by. A second phase is about to start. In the meantime the first phase of MUSHROOMS is happening.


Can I expect a cure? Probably not. Could they help other parts of MS? Perhaps, perhaps not.

I am talking of just some certain strains, that my neurologist knows others with MS are trying.  Its like a blind study, using the real mushrooms. You can study up on them, their technical items.

I will try blogging about each strain, perhaps the names, and technical usage expected or experience with the Mushroom, as I take one or combination  or of different Mushroom combinations.


Now, you can not just go out and buy the Mushroom to eat. Does not work that way.

Like other herbs used, the extraction process is a key factor. Some off the ones I found have done this for you.

 Exracted with hot water and alcohol (dual extraction) must take place


You can find many mushrooms on the internet.  Make sure you are getting high quality pills or powder to use. These can be added to smoothies, coffee, baking, ect.

  • Made from 100% organic mushrooms
  • Extracted with hot water and alcohol (dual extraction)
  • Made from Certified Organic mushrooms
  • Gluten-Free, Non-GMO, Vegan
  • >15% Beta-glucans, >4% Triterpenes
  • No added starch, mycelium, or grain of any kind
  • Verified for quality at accredited 3rd party labs


As always, I am not a medical Doctor, and Mushrooms need to be gone over with your Doctor.


I found a few sites quite quick that have Real Mushrooms. Let me know if their are better sites to buy from.





Science Direct has interesting article, as it applies to MS and pathways that get broken by this disease.

Therapeutic applications of mushrooms and their biomolecules along with a glimpse of in silico approach in neurodegenerative diseases

https://www.sciencedirect.com/science/article/pii/S0753332221001621#:%7E:text=It%20reported%20that%20many%20mushroom,attacked%20by%20the%20immune%20system



Lion’s mane and multiple sclerosis: Is it effective?

Medically reviewed by Heidi Moawad, M.D. — By Caitlin Geng on August 

https://www.medicalnewstoday.com/articles/lions-mane-and-multiple-sclerosis



And of course Dr Terry Wahls,MD

https://terrywahls.com/ms-management-and-my-medicinal-mushroom-trio/



Thanks for reading.

Join my Facebook page,

Leave me a message

joey

Everchangingms@gmail.com

Sunday, September 4, 2022

Multiple Sclerosis 2022 has a year made it thru?

 



Seems my blogs get far and few.  Many reasons. More Specialized Doctors added, some top of the top working with me.  I had the pleasure of meeting one, who came out of retirement, to work his specialized clinic once per month. A six month wait to get to talk with the Dr, and two others, plus student learning, as I was listening also.

These Drs specifically specialize in one field. Like one box you do not stray from. So he did not know of other diseases, just generally.  I was his first MS Patient in all his years.

Excellent at his knowledge. That was what he was teaching me in the hour spent. He did a lot of reflexes and watched me walk, talk, movements.  A new toy to "try" for five minutes a day, perhaps 15 minutes.  That was the only thing left he could offer.

My MS specialist is awaiting a new mylan repair medicine.

The Day before, I saw my MS Botox neurologist. He had a new Dr with him. I let the new Dr put the botox into my muscles. He was not afraid to ask for assistance finding muscles, asking my main Dr there. I look forward, as these shots help me stay active and walking.   I have to sign a Black Box Warning for this medivine.

I have been seeing this top dr in his field and his co Specialist and his team for this last year. They were able to bring my blood pressure and all readings into a normal range. half of what it was.


 I brought my iron up into normal range, by stopping curcumin turmeric for a day, eating beef liver ( high in Iron ) and back onto supplement. Retested, and my being iron deficient for three years after my phlebotomy or vein puncture, all went away.


                                                         Yes a DROP in blood readings

Now I am not a Dr, but would of liked to of been a birdie listening in on how Drs (in their own boxes) can disagree on symptoms and what even their test may say is going on with me.  The phone call to all these other Experts in their own field., and their perspective, or what left is a option.

All I can share now is I have Primary Progressive Multiple Sclerosis. This is effecting my whole body, in ways I would never imagine. Hereditary Hemochromatosis with the H63D H63D gene playing a role, overlapping Endocrinologist, hematologist, Neurologist,GI, nephrologis,, and 23 more to list. That are overseeing My Multiple Sclerosis. A good team. The Best of the Best.

I still walk with a cane. Minds active. get around, fatige real easily.   Research what Dr, their thoughts, brings me back to a reality, shared with only a few this entire year, of what they see, or know.  The changes a reality.


Thanks for reading 

Joey

,

Wednesday, August 17, 2022

Vitamin D and coimbra protocol

 

I can not say this better than the source. I've mentioned this in the past, but its been a while ago.






Vitamin D and coimbra protocol



https://www.coimbraprotocol.com/general-information


https://www.coimbraprotocol.com/general-information





Sunday, July 24, 2022

IRON. IRON H63D gene Hereditary Hemochromatosis

      Its been a while, but refresher course in iron.   A double H63D gene was found  in 2018. A rare for it to overload iron over load, but did. 17 trips to phlebotomist, or vein puncture, to take blood from me. see prior posts.

Do labs every three months. I was left iron deficient for three years. I found if I stopped my turmeric curcumin regime  a day, and ate beef liver with onions, and restarted my regime, it brought my iron back into balance in 2022. A trial and experiment.

 As there had to be a way to close the iron valve.

Since I have Primary Progressive Multiple Sclerosis, some items get blamed, where there may be a different diagnosis. So thus bouncing between Drs, who all have their own theory.  Last October 2021, my hemoglobin was high again. To many red blood cells, or to large.  Thus prior you tube videos to explain. But No Iron to dispose of with a phlebotomy. 2022 was year I got iron increased, by trial. And testing.  A three year low, or anemia that played a part.

Labs again in a few months, to check, and double check endocrine system. A protocol, a Specialist put me on last year  in 2021 helps tremedously but that's for another blog.

I receive Botox every three months. Injected deep into calves, inside and out, thigh muscles, and into neck muscles on both sides, and into right shoulder. The right arm was added last time.  Another blog to talk about, but helps a great deal.


But I did not want to loose these links that help understand... Just more info to listen to.

        

Iron Deficiency Without Anemia – Common, Important, Neglected



        Transferrin   Saturation





Another great site I found on iron, and related diseases

http://checkiron.com


                                                       Iron Physiology





Gastrointestinal | Liver Metabolism, Protein Synthesis & Storage


   


Approach to Anemia


Join my blog, so I know my readers!

JoeY

Wednesday, July 20, 2022

Neurologist and specialized Drs

 






Every Dr has their Speciality that I see for multiple conditions. The year 2022, made it this far with Primary progressive Multiple Sclerosis.  Awaiting new medicine to come out, as my body makes everything off the table, except Copaxone and twenty plus medicines.

So I stick to what is working thru my lengthy list of medicines, and what they are used for. Vitamin D3 in high doses, followed by endocrinologist every three months. A GI Dr, A Kidney Dr, A Heart Dr, a blood Dr, a endocrinologist, Eye drs, The list goes on.

A B12 test was ordered to check my levels, as they were low a few years ago. This you pee out any extra.  I see my blood Dr in a few weeks, as B12 can also make more red blood cells. I wonder about my other B vitamins. I do not need more red blood cells, as that makes more hemoglobin, which in turn bounces me back to another Dr.

I was on high dosage of Biotin a few years back, vitamin B7.  I measured pure powder on a scale, following study, but on real biotin, followed by endocrinologist.  The vitamin affects many lab test, and I had to stop for my endocrinologist. The high dose biotin trial, never panned out with good results anyways.

Currently my labs look good, but adding in certain vitamins could cause problems.  I have hereditary Hemochromatosis, with the Rare H63D genes, both gave me iron overload in 2018/9.  I did 17 phlebotomy or veinpuncture to resolve the iron, but that left me iron deficiency for three years. That has its own set of problems, of Anemia, and items shown how blood is made from the bones.  I will have to go into detail in another blog.


Anyways, being unique in getting all the side effects of medicines, especially generic, My team works hard to ensure I stay on name brand.

A Testosterone test came back with erroneous readings. My Dr thought the batch that my pharmacy sent was bad. She made three attempts at over a hour each to get a replacement medication.  They decided to play Dr, and Not Send any new unit, so I could retest. Every day she sent a new prescription in, talking to pharmaceutical department, it put them shipping out the next 90 day order by a few days, of when my regular order was due. Three long emails were sent from me also about the problem, that they answered to call them again.  This comes to who is playing Dr.  

My three month labs will come due, right before my next shipment comes. A waste of resources, from the drs, the labs, The largest mail order pharmacy. They asked if I wanted to file a complaint. Hmm.. "Like bitting the tail of the Dragon that feeds you"



Photo credit wixmp.com

Back to Experts I utilize at UC Davis, Sacramento. Many items have been added to my MS over the last ten years.  I lost count, at over twenty experts looking into certain areas that has a cause and effect.  I do much research giving experts a a different viewpoint sometimes on new studies or of which came first, as their is no cure.
This blog, to help keep scientist and followers updated to a point.


A lot has gone on this last year, I may write about in another blog, but being bounced around like a ping ball between Drs right now. Just not much research has been found because of my unique mess, of different specialists needed. Was offered two new ones, but have declined until I get my other specialists updated and involved.  
Everything takes time.



Joey



Sunday, June 19, 2022

State of California vs Joe lawsuit





Most of you know I live in California. How can I afford items is still a mystery.

We live quite Rural at 3,000 ft above Volcano CA pop 101. Beautiful in nature with a small home, and no close neighbors. 

I went thru so many state and federal programs before my diagnosis was found.

Years without any income coming in.  I was glad to have a house with my partner to stay in, and not be on the streets. I have two moms. My partners Mom, who takes excellent care of me, and my mom, who lives in Alaska, who also is quite supportive. Bruce was my partners dad, quite knowledgeable. Miss him, and our conversations. He had been bedridden for 30+ years.  My partner is quite supportive and helpful with me.

I was diagnosed in 2012 with Primary Progressive Multiple Sclerosis.

Many rides were needed to go to Doctors outside our county. This includes The University of California Davis in Sacramento, CA. This can be up to a two hour ride one way.

Our county is smal, and does not attract to many good doctors, I hope you all do your own investigating, and can find expert cae, even if its in the next county with knowledgeable Doctors.  My local GP knew something was going on, and knew the only neurologist had not gone far enough. He sent me to a Neurologist outside or County for care.


I am on a dual medi-medi program from the Federal Government, State Government, and Social security.

The State of California made a ruling years ago, that makes sure you get to and from your Dr visits, by providing rides. This applies to anyone on Medicaid, or Medi-Cal or certain other programs. The state maintains a huge fleet contracted out. "All you do is have to call them" ...not so easy.


"The State of California is Required to provide me with transportation to and from  all of my doctors. This is something not happening...

John Tan of  Legal Services of Northern CA has taken this to court twice.
42 C.F.R. 431.53 requires Medicaid plans to specify that "Medicaid agency will ensure necessary transportation for participants to and from providers" transportation includes rides but also "expenses for transportation and other related expenses...". 42.CFR 440.170(A)(1) Fee For Services... Cal. Welf. And instead code 14132(ad)(2)(B)
A State hearing before Judge Hammond was heard in Sacramento, CA March 26, 2019, and a re hearing was heard July 16, 2019. Both denied.


Legal services of Northern CA has appealed this case March 18, 2020. Due to the world Epidemic, the case is dragging on.  Natalie DaSilvia  is in charge.  the year is 2022.  when she left,Ted Mumford took over 
tmumford@lsnc.net
 


He is the leader of this ongoing court case in 2022

This state mandate took nine years to find, going thru counties, government, agencies, other organizations, and many counties. to find. organisations who gives rides, but they would not for me.  

The year found, 2018 was that in the next small town, Ione, CA, was Hector from foothills medical transportation. Nobody in any State agency knew of him, or that he gave rides. There are five NEMT (Non Emergency Medical Transportation) in the state. Contacting DHCS,(Department of Health Care Services) took them nine years to find Hector for me.

 This came from a Sacramento Government Agency, who knew of the problem. They had been contacted many times before, with no response.


To this Date, 40,000 people in Amador County need to be on a ppo plan, as no HMO is in the area, unless you forge that you live in ione, ca. That gets you to a hmo, keiser in the valley, another county away. 2023 you are required to join a HMO.

If on a HMO, there is not a problem with rides, they say. . Many vehicles, and companies can give.  the State of California has a huge fleet of vehicle's that they use, pay the drivers, wait time, so to take you home is what is supposed to happen.  Our county will not tell you rides are availiable.

Hector can only drive on certain days, as I am the only one in Amador county that needs rides?...   

The lawsuit needs to charge each county not being in compliance and letting their clients know of the service, that they can get to And from doctors. Perhaps sue counties also for non compliance


Currently, to try and obtain a ride, I must submit a request to 
The Department of Health care services.  My Dr, What for, address, ect.  I also send this to my county workers, who should know about the program, but fail to let clients know. At one point, the county said travel reimbursement, but I have seen zero. The County personnel also wanted Hippa Privacy items, not entitled to, to be sent.

I keep this list, published here also, so I will not forget who I send requests for rides to.

They usually are ignored, not responded from, or go  un-noticed.


tmumford@lsnc.net

Ted Mumford, lsnc.net


Hector Flores

foothillsmedicaltransportation@gmail.com

TMitchell@amadorgov.org

Jrodriguez@amadorgov.org

TDalporto@amadorgov.org

Matthew.Kizzie@dhcs.ca.gov ended employment 5/20/22

Jonathan.Ring@dhcs.ca.gov

Tiffany.Saelee@dhcs.ca.gov

Tere Gonzalez  Tere.Gonzalez@dhcs.ca.gov

Jim.Elliott@dhcs.ca.gov





The State of California VS Joe leighkendall was heard by a Judge, earlier this year, as required for transportation. The State has asked for two delays, which were granted. They used this to abuse their powers by auditing Hector, his books, and vehicles he uses.

They did not audit anybody else.

To ensure his fleet was spick and span, records up to date.

 I asked DHCS for reimbursement for my partner,  Our 29 year old vehicles have taken a beating. Wil can not drive the distance. Records from doctors from 2012 of rides needed were given to all for reimbursement. All current ones are emailed to the above. . I have exhausted all means of transportation.


 I asked for transportation to out of town doctors. gas reimbursement, registration fees, insurance fees, repair cost and operating costs. A repair of the system.


I asked them to comply with their rules and supply me with a driver to get me to and from Doctors out of Amador County , as required.  

I asked that other people in my situation, have access who qualify, with reimbursement for anything else related.

I asked them to Fix their system, so thousands of others that qualify, or are enrolled and qualify, can get rides, uber, lyft, (we are to small to have that luxery of paid cars to take you places) so need a driver like Hector. He has vehicles, and drives many people on hmo plans.  reimbursement, and everything that the DHCS offers.  Rides to and from the Dr, medical trips, supplies. He has vehicles ready to hire more drivers, but I am the only one that has researched, taking time being pro active.

Hector can only drive me on certain days. My Doctors do not allow me to choose dates. As they only see patients on certain days. He takes many patients to dialysis, thus he has a filled schedule.

The year, 2018, not looking for another diagnosis, my Endocrinologist sent me to the Cancer Doctor at UC Davis, as  blood readings kept being off.   The cancer Dr. did some gene testing, ruling some out, before he found the HFE Gene, a Rare H63d Gene causing Iron Overload in me. Quite Rare, and I  have only found a few other persons in a ten year span that have iron overloaded.


This caused 17 phlebotomy to uc davis weekly, along with trips to my other Doctors. The only treatment is barberic, known as blood letting or a Phlebotomy weekly, to drain blood from me, trying to get the iron down.  My blood comes out as thick as pancake batter.

No rides given, even though the State DHCS knew about the real need, as exhausted all other means.

2019

John Tan of  Legal Services of Northern CA has taken this to court twice.

The State of California VS Joe leighkendall was heard by a Judge, earlier this year, as required for transportation. The State has asked for two delays, which were granted. They used this to abuse their powers by auditing Hector, his books, and vehicles he uses.

 I asked for reimbursement for Wil, who had driven, 

A  hearing by a different Judge was asked for On terms CA was not following their own rules.  The first judge took fifteen pages to state denial. The second judge did not override any items.


CA IS NOT FOLLOWING ITS OWN RULES, as I am Not on a Managed care plan, and Can not be. Must be on a PPO plan, because of all the specialist, and No HMO plan covers our county.

On Sunday August 11 On page 6a of the Sacramento Bee, Cathhie  Anderson wrote a excellent article that blast medi-cal for failing 18 counties, and she doesn't know people on Nemt, have been forgotten, and No rides given, or re reimbursed for. .This  Took DHCS  Nine years, and then another three months to find me a driver 15 miles from home, taking the largest toll on trying to keep a vehicle running for multiple specialists weekly, and a Toll on Wil trying to maneuver Sacramento.

The State says they do not have a reimbursement plan in place, but they do, just a code Needs added to their existing transportation for those of us forgotten patients.   That would pay Nemt (non emergency medical transportation) drivers , the same premiums that the state's drivers are paid ( they pay a lower rate currently) , and wait time, to go hundreds of miles, reimbursement for mileage Wil drove, plus maintenance, and, would love new vehicle that is safe for local Doctors.


UPDATE OCTOBER 2020
this case is being heard by the California Attorney General.  They just want this to go away...

This is being handled by legal services of northern California for me.

I would need a Second Class Action Attorney to represent thousand not receiving this benefit.

I did Not accept their offer, as Rides to appointments are still needed to Sacramento. Rides Wil can not drive.

Local rides, I asked for the excess repair needing done, including a timing belt, tires,and engine repair on old vehicles. A Driver the state has, like Hector, and wages paid in accordance.

I would like this to be not just me, but open the door for others that can not receive rides to their Drs, as I am not on a HMO plan, that guarantees rides, reimbursement for lyft, uber, taxis, and any form of ride, regardless.  This is Stated in CA Law.


Know I am remote, but many people are in same predicament, in the entire state of California in small rural areas, or small counties forgotten.


For all hose that do not know, DHCS sub contracts out to a huge driver van service used to move people to Drs and  back home. If not, the people can hire lyft, taxis, for reimbursement. That is not a option for us in our small county, thus requested out of town rides provided by state.


​​​Transportation Services

Medi-Cal offers transportation to and from appointments for services covered by Medi-Cal. This includes transportation to medical, dental, mental health, or substance use disorder appointments, and to pick up prescriptions and medical supplies.
 
There are two types of transportation for appointments. Nonemergency medical transportation (NEMT) is transportation by ambulance, wheelchair van, or litter van for those who cannot use public or private transportation. Nonmedical transportation (NMT) is transportation by private or public vehicle for people who do not have another way to get to their appointment.
 
When requesting transportation, be sure to contact the transportation provider as soon as you can before an appointment. If you have many appointments, you can also request transportation to cover those appointments.

https://www.dhcs.ca.gov/services/medi-cal/Pages/Transportation.aspx



Hector from  foothillsmedicaltransportation.com was contracted to drive us, but missed many rides.  He has my medical Dr list for next six months, along with everyone on the email list above. 

so I hope he can still help on some rides.. 

Their is expensive rides in hundreds of dollars, people would charge, just to be denied they are not on DHCS registry, and I would not be reimbursed that I was asked to take.

We live at 3,000 ft elevation that gets Snow in Amador County.

The State of California is Required to provide me with transportation to all of my doctors. This is something not happening. 

 . I asked for reimbursement for Wil.
 I asked for transportation to out of town doctors.
I asked for the wait time, and to be able for second appointment the same day paid for, as the state caps the wait time for Hector at a minimum wage when he can drive.

Some appointments are more than the hour allotted, being a few hours, or waits between two Drs on the same day

In the meantime, Hector has stepped in to help out of town driving, per agreement with the State. But not many fit his schedule.

 I have exhausted all possibilities of other rides.


Hopefully this will find its hands into the proper State, County, Federal people to see that their program failed me, along with thousands of others, that do not know, or are not told about this. 

 Even Hector could hire another Driver if others in Amador County knew of the Rides to and From Drs even outside of our small county to obtain expert Doctors needed.

Contact me everchangingms@gmail.com, or my legal team, tmumford@lsnc.net for answers.


Thanks for reading my rant

This message (and any associated files) is intended only for the use of

the individual or entity to which it is addressed and may contain

information that is confidential, subject to copyright or constitutes

a trade secret. If you are not the intended recipient you are hereby

notified that any dissemination, copying or distribution of this message,

or files associated with this message, is strictly prohibited. If you

have received this message in error, please notify us immediately

by replying to the message and deleting it from your computer.

Messages sent to and from us may be monitored.


Internet communications cannot be guaranteed to be secure or error-free

as information could be intercepted, corrupted, lost, destroyed, arrive

late or incomplete, or contain viruses. Therefore, we do not accept

responsibility for any errors or omissions that are present in this

message, or any attachment, that have arisen as a result of e-mail transmission.

If verification is required, please request a hard-copy version.

Any views or opinions presented are solely those of the author and do not

necessarily represent those of anyone or entity

The information expressed and any attachments may be privileged or confidential, and may not be factual in any court cases. In no means should it be used against plaintiffs for opinions expressed.   If you are not the intended recipient, please delete the above and any attachments and notify the sender immediately or call Legal Services of Northern California at 916-551-2150.

Joe


This Last year, 2022, Hector has been unable to make any rides., except two on a friday/Saturday.

DHCS Requires in 2023 Everyone be on a HMO plan. Drs in our county do not accept this plan. You can call the list provided, and will not get a Dr, or Hospital. 

DHCS required me to ask to a Exemption from UC davis. One filed, but forms kept coming to join a HMO. A second Exemption of 75 pages was filed by my Dr. Then DHCS accepted this, and then stated I did not need, as was Exempt from joining a HMO.

The latest hearing, DHCS is being required to turn over a list of everyone driven in CA, and how they pay drivers, reimbursement. Still dragging on.

On a note Kiser was given the HMO contract in 2024 for Amador County. ( no bidding?) Or Drivers to take care of need Now?



Wednesday, April 6, 2022

Sleep and MS, or Sleep awake Cycle, sleep deprivation



 A Topic, I have not blogged much on, is the sleep cycle. There is a known item called Sleep deprivation also.

I have experienced this since before being diagnosed with Multiple Sclerosis. But this is part of Multiple Sclerosis, and a bunch of other disorders.


This According to Wikipedia, 

"Sleep is a naturally recurring state of mind and body, characterized by altered consciousness, relatively inhibited sensory activity, reduced muscle activity and inhibition of nearly all voluntary muscles during rapid eye movement (REM) sleep,[1] and reduced interactions with surroundings.[2] It is distinguished from wakefulness by a decreased ability to react to stimuli, but more reactive than a coma or disorders of consciousness, with sleep displaying different, active brain patterns.

A sleeping girl
Sleep is associated with a state of muscle relaxation and reduced perception of environmental stimuli.

Sleep occurs in repeating periods, in which the body alternates between two distinct modes: REM sleep and non-REM sleep. Although REM stands for "rapid eye movement", this mode of sleep has many other aspects, including virtual paralysis of the body. A well-known feature of sleep is the dream, an experience typically recounted in narrative form, which resembles waking life while in progress, but which usually can later be distinguished as fantasy. During sleep, most of the body's systems are in an anabolic state, helping to restore the immunenervousskeletal, and muscular systems;[3] these are vital processes that maintain mood, memory, and cognitive function, and play a large role in the function of the endocrine and immune systems.[4] The internal circadian clock promotes sleep daily at night. The diverse purposes and mechanisms of sleep are the subject of substantial ongoing research.[5] Sleep is a highly conserved behavior across animal evolution.[6]"


I can only tell you of my experience of sleep with being diagnosed with multiple sclerosis.  I am not a Doctor, but rely on them with many questions.

Most over the counter items have been tried. Check with your Doctor, before doing this, as some may interact with medicines.

Many multiple sclerosis medicines will can make you sleepy.  But being able to sleep at the right time is a necessary evil that can transform into sleep deprivation.

I even tried items to help you sleep. Many are availiable by Google search, or youtube.com  binerial  beats at different frequencies was interesting. The sleep talk, to make you feel sleepy, or the pitter patter of rain drops, to the ocean, or a campfire sometimes helps.  Making sure your room is for sleep.

"Sleep timing depends greatly on hormonal signals from the circadian clock, or Process C, a complex neurochemical system which uses signals from an organism's environment to recreate an internal day–night rhythm. Process C counteracts the homeostatic drive for sleep during the day (in diurnal animals) and augments it at night.[27][23] The suprachiasmatic nucleus (SCN), a brain area directly above the optic chiasm, is presently considered the most important nexus for this process; however, secondary clock systems have been found throughout the body."

My circadian clock was real messed up.

But when all these fail, your Doctor may prescribe medicines. Drug companies may have you do what they call "Step Therapy".  This is usually a process to make you fail, using inferior medications, perhaps a copy of the real medicine, or combinations.

After using a dozen, perhaps more, that included lunesta, and many other  generic sleep meds. at least thirteen other companies make this. All they need is 75% of the active ingredient for a generic medication. I was switched to many sub standard companies, before I requested name brand Ambie, then went to Ambien ER in 2013.

This has happened with other meds that went to generic versions.  Some had detrimental effects on me, that I need the name brand.

Recently, the worlds largest pharmaceutical company bought out contracts from other boxed stores, making them the only player for the consumer to buy from. They Stopped carrying Ambien, with a phone call from their customer service Center, asking me, what I wanted to switch to. I asked if she was a dr, and she said no. I told her I was not a Dr either, so she would have to contact my Dr.

The largest company, Express Scripts, was just bought out by Cigna.

Then it started all over, of "Step Therapy Medications". Three were mentioned. I had already tried. Meds to treat my Multiple Sclerosis were stronger than the Three, per ingredients, and some would interfere with my regimen of meds. I quoted some legal items of Step Therapy to my Dr. For help of obtaining something better.

I gave her two new sleep medicines, and a third coming out, that might replace, or be as strong as Ambien, and the research sites of how they work.

DAYVIGO was chosen, and needed prior authorization, medical exemptions, which were quickly denied.  More paperwork for all the above.  This is where a insurance becomes a Dr without a license.  A review committee, and finally a approval for my Doctor.

5 mg was not strong enough a week later, so my Dr requested 10 mg.

This works differently than ambien. But will have to let you know. I keep a sleep tracker on my watch, a inspire. It gives me scores of sleep, deep, light, Rem, and much more information I  can show my Doctor. Example below.


Much more information is availiable. Many watches and apps were tried, before this was purchased, which show sleep. 


Quviviq-new-sleeping-pill is the newest sleep aid being tried, June 2022. Clicking on this will give you more info than I can, and I will have to do a update on each of these pills.

DAYVIGO gave me vivid dreams, but the maximum dose still did not get me the Quality of sleep I need.

I have been to three sleep studies, two overnight at UC Davis. Many electrodes placed on your head and body. its like being cloned, as they measure all these elements.  I do not have sleep apnea, a condition of snoring. A Cpap machine helps many.

I think I am a test subject, due to my primary progressive Multiple Sclerosis, and hereditary Hemochromatosis caused by two rare DNA H63D genes, that caused Iron Overload.

my regimen consist of over twenty Nine medications, counted out for daily use. Each designed for the multitude of MS symptoms, and therapies that have been added on... including Botox  into my calves, thighs, neck and shoulder muscles. Many of the meds make me sleepy, so to combat that Prohibit is used during the day, to give me a few hours for the quality of life.

Thanks for reading.

Email me with questions anytime.

JoeY