Vitamin B and what is effected in MS with DNA

 

Vitamin B

Image from Wikipedia

B1 is used for Metabolism.  According to Wikipedia, "Thiamine, also known as thiamin and vitamin B₁, is a vitamin, an essential micronutrient, that cannot be made in the body.^[3][4] It is found in food and commercially synthesized to be a dietary supplement or medication.^[1][5] Phosphorylated forms of thiamine are required for some metabolic reactions, including the breakdown of glucose and amino acids.^[1] "

B2,  Riboflavin, also known as vitamin B2, is a vitamin found in food and sold as a dietary supplement. It is essential to the formation of two major coenzymes...f!avin mononucleotide and flavin adenine dinucleotide  What is riboflavin and what does it do? Riboflavin (also called vitamin B2) is important for the growth, development, and function of the cells in your body. It also helps turn the food you eat into the energy you need.

B3 Niacin. It can treat high cholesterol and triglyceride levels as well as niacin deficiency. It can also reduce the risk of heart attack and slow narrowing of the arteries.

Overview. Niacin is a B vitamin that's made and used by your body to turn food into energy. It helps keep your nervous system, digestive system and skin healthy.

 key difference between vitamin B3 and B12 is that vitamin B3 is important in controlling cholesterol and triglyceride levels in our blood, whereas vitamin B12 is important as a cofactor in DNA synthesis for both fatty acid and amino acid metabolism.Niacin, also known as vitamin B3, is an important nutrient. In fact, every part of your body needs it to function properly. As a supplement, niacin may help lower cholesterol, ease arthritis, and boost brain function, among other benefits.

May reduce blood pressure. One role of niacin is to release prostaglandins, or chemicals that help your blood vessels widen — improving blood flow and reducing blood pressure. For this reason, niacin may play a role in the prevention or treatment of high blood pressure 

Vitamin B3 is a member of the vitamin family, which includes three forms of vitamers as nicotinamide, niacin, and nicotinamide riboside. Vitamin B12 is a type of vitamin involved in metabolism in our body.

what-is-the-difference-between-niacin-niacinamide/

B5. Pantothenic acid, also called vitamin B₅ is a water-soluble B vitamin and therefore an essential nutrient. All animals require pantothenic acid in order to synthesize coenzyme A – essential for fatty acid metabolism – as well as to, in general, synthesize and metabolize proteins, carbohydrates, and fats     what is B5 vitamins good for? In addition to playing a role in the breakdown of fats and carbohydrates for energy, vitamin B5 is critical to the manufacture of red blood cells, as well as sex and stress-related hormones produced in the adrenal glands, small glands that sit atop the kidneys.

B6. Vitamin B-6 pyridoxine is important for normal brain development and for keeping the nervous system and immune system healthy. Food sources of vitamin B-6 include poultry, fish, potatoes, chickpeas, bananas and fortified cereals Vitamin B6 is a vitamin that benefits the central nervous system and metabolism. Its roles include turning food into energy and helping to create neurotransmitters, such as serotonin and dopamine.Vitamin B6 is one of eight B vitamins. This group of vitamins is important for proper cell function. They help with metabolism, creating blood cells, and keeping cells healthy.  also known as pyridoxine, vitamin B6 is a water-soluble vitamin, which means it dissolves in water. The body does not store vitamin B6 and releases any excess in urine, so people need to get enough vitamin B6 every day.

B9  Folic Acid.  aids in the production of DNA and RNA, the body's genetic material, and is especially important when cells and tissues are growing rapidly, such as in infancy, adolescence, and pregnancy. Folic acid also works closely with vitamin B12 to help make red blood cells and help iron work properly in the body.

Vitamin B9, also called folate or folic acid, is one of 8 B vitamins. All B vitamins help the body convert food (carbohydrates) into fuel (glucose), which is used to produce energy.

What happens when you lack B9? Vitamin B9 deficiency can lead to anaemia and might increase your risk of heart disease. It's also really important during early pregnancy for a developing baby. Signs of deficiency include tiredness, weakness, shortness of breath, heart palpitations, and difficulty concentrating.

When you have anemia, your blood can't bring enough oxygen to all your tissues and organs. Without enough oxygen, your body can't work as well as it should. Low levels of folic acid can cause megaloblastic anemia. With this condition, red blood cells are larger than normal. It works wit B12

Folic acid helps make healthy red blood cells, which carry oxygen around the body. If you do not have enough folic acid, your body can make abnormally large red blood cells that do not work properly. This causes folate deficiency anaemia, which can cause tiredness and other symptoms.

What is Methyl Folate?
Methylfolate, sometimes known as L Methylfolate or 5-MTHF, is the active, more bioavailable form of the essential B-Vitamin Folic Acid. In order for the body to use Folic Acid, it must first be converted to Methyl Folate. 

Folic acid and folate can be cheap, but methylfolate tends to be the most effective option when it comes to treating the unique needs of MTHFR and giving the body an enzyme it can directly act upon. L-methylfolate (chemically (6S)-5-Methyltetrahydrofolate) is the most pure, active form of methylfolate you can buy.

B12 Vitamin B₁₂, also known as cobalamin, is a water-soluble vitamin involved in metabolism. It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, in both fatty acid and amino acid metabolism. Wikipedia. 

Vitamin B12 is a nutrient that helps keep your body's blood and nerve cells healthy and helps make DNA, the genetic material in all of your cells. Vitamin B12 also helps prevent megaloblastic anemia, a blood condition that makes people tired and weak

Methylcobalamin. Methylcobalamin is the most bio-available type of Vitamin B12 which means the body absorbs it more easily. Naturally occurring, it is found in animal-based foods such as meat, fish, milk and eggs

People sometimes ask which of the two supplements is better – the artificial (cyanocobalamin) or naturally occurring (methylcobalamin). Studies have shown that cyanocobalamin is known to absorb slightly better within the body while methylcobalamin is considered to retain better and for longer.Aug 23, 2022.

t, and eat thru your gut.ry

DNA. mthfre Gene

The MTHFR gene codes for a key 

enzyme in folate metabolism

I just so happen to have this Gene, and wrote about it before I found out I was Vitamin Deficiency of B12.  I am below 200. Neurologist wants me above 800. I went thru my entire team, to ensure the individual combinations might be of help.  It may be a double edge sword though, as thick blood cells become problematic.

Methylenetetrahydrofolate reductase deficiency is the most common genetic cause of elevated serum levels of homocysteine (hyperhomocysteinemia). It is caused by genetic defects in MTHFR, which is an important enzyme in the methyl cycle.^[1]

Thanks for reading.

Hope this will let you question each vitamin, and amount used, and why.

I did not go into full details, but a starting point.

Energy Drinks full of only certain B vitamins, that may not be the best to try

My Dr also agreed, that if I'm deficient in b12, that I am deficient in other B Vitamins.

I am not a Doctor, so check with yours before taking any supplements. Some may interfere with other meds.

A few of ones to start with. Vitamin B7, or Biotin, i stayed away from, as it effects blood test

B1 250mg metabolism

B2 as Riboflavin 100mg

B3 as Niacin 500 mg

B5 as Pantothenic Acid 500 Mg

B6 100 mg Metabolism support

B9 800 Mcg as folic Acid

B9 Methylfolate

B12 as Methylcobalamin 2000 mcg

B12 as cyanocobalamin 3000